Determining friction is as equally essential as determining the film thickness in the lubricated contact, and is an important research subject. Indeed, reduction of friction in the automotive industry is important for both the minimization of fuel consumption as well as the decrease in the emissions of greenhouse gases. However, the progress in friction reduction has been limited by the difficulty in understanding the mechanism of roughness effects on friction. It was observed that micro-surface geometry or roughness was one of the major factors that affected the friction coefficient. In the present study, a new methodology coupling the multiscale decomposition of the surface and the prediction of the friction coefficient by numerical simulation was developed to understand the influence of the scale of roughness in the friction coefficient. In particular, the real surface decomposed in different roughness scale by multiscale decomposition, based on ridgelets transform, was used as input into the model. This model predicts the effect of scale on mixed elastohydroynamic point contact. The results indicate a good influence of the fine scale of surface roughness on the friction coefficient for full-film lubrication as well as a beginning of improvement for mixed lubrication.