Journal misalignment usually exists in journal bearings that affect nearly all the bearings static and dynamic characteristics including minimum oil film thickness, maximum oil film pressure, maximum oil film temperature, oil film stiffness, and damping. The main point in this study is to provide a comprehensive analysis on the oil film pressure, oil film temperature, oil film thickness, load-carrying capacity, oil film stiffness, and damping of journal bearing with different misalignment ratios and appropriately considering the turbulent and thermo effects based on solving the generalized Reynolds equation and energy equation. The results indicate that the oil thermo effects have a significant effect on the lubrication of misaligned journal bearings under large eccentricity ratio. The turbulent will obviously affect the lubrication of misaligned journal bearings when the eccentricity or misalignment ratio is large. In the present design of the journal bearing, the load and speed become higher and higher, and the eccentricity and misalignment ratio are usually large in the operating conditions. Therefore, it is necessary to take the effects of journal misalignment, turbulent, and thermal effect into account in the design and analysis of journal bearings.